Correlation of NIRS Measurements of Tissue Oxygen Saturation with Transcutaneous pO2 in Patients with Chronic Wounds
SnapshotNIR uses NIR (Near-Infrared) light to determine tissue oxygenation saturation (StO2), one of the key indicators of tissue health. NIR light penetrates ~2-3mm into the tissue, making it ideal for microcirculation assessment, where oxygen exchange is happening. Key Publications in Wound Care covers some of the most up-to-date research on the use of Kent Imaging’s SnapshotNIR in the areas of wound care and limb preservation.
Correlation of Near-Infrared Spectroscopy Measurements of Tissue Oxygen Saturation with Transcutaneous pO2 in Patients with Chronic Wounds. 2016; SM Vasc Med; 1(2): 100.
Bowen, R.E., Treadwell, G.R.N., Goodwin, M.R.R.T.
CLINICAL DATA
Background: Assessment of tissue oxygenation and vascular function is an integral component in the management of chronic wounds. Current practice in wound centers is screening with Pulse Volume Recording (PVR) or Transcutaneous Oxygen Saturation (tcpO2) to evaluate the safety of compression wraps, the utility for vascular intervention, and expected response to Hyperbaric Oxygen Therapy (HBOT).
A near-infrared spectroscopy (NIRS) device (Kent Imaging, Calgary) using 4 wavelengths of light to determine the oxygen saturation of hemoglobin (Hgb) in cutaneous tissue has been developed. The low absorption of light by H2O and melanin in the NIR range allows for the measurement of absorption of deoxygenated and oxygenated Hgb and for the calculation of oxygen saturation (StO2). The purpose of this study is to determine the correlation between the gold standard tcpO2 and NIRS in measuring cutaneous oxygen.
Materials and Methods: 20 patients with Fitzpatrick skin types I-III who had measurements of tcpO2 (Perimed, Stockholm) also had simultaneous measurements obtained by NIRS.
Graph recreated from Bowen, R.E., Treadwell, G.R.N., Goodwin, M.R.R.T. 2016
Conclusions: There was a significant correlation between measurements of tissue oxygenation using tcpO2 and NIRS. NIRS has the advantage of not requiring skin contact and measurements can be taken in the wound bed. Other advantages include 1. Time (2 minutes vs. 90 minutes); 2. Disposable cost ($150 – tcpO2 vs. $0 – NIRS); 3. The ability to perform serial studies over time.
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